T37T (p.Thr37Thr) variant of PLCG2 (P16885)
T37T (p.Thr37Thr) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T37T (p.Thr37Thr) variant details
- p.Thr37Thr
- rs762280295
- gnomAD 16-81786100-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0996
- CADD 2.68
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.301
- Literature evidence available