T26T (p.Thr26Thr) variant of PLCG2 (P16885)
T26T (p.Thr26Thr) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T26T (p.Thr26Thr) variant details
- p.Thr26Thr
- rs749437141
- gnomAD 16-81786067-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.105
- CADD 3.45
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.121
- Literature evidence available