S9S (p.Ser9Ser) variant of PLCG2 (P16885)
S9S (p.Ser9Ser) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S9S (p.Ser9Ser) variant details
- p.Ser9Ser
- rs772778136
- gnomAD 16-81786016-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.235
- CADD 5.98
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.223
- Literature evidence available