S2S (p.Ser2Ser) variant of PLCG2 (P16885)
S2S (p.Ser2Ser) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S2S (p.Ser2Ser) variant details
- p.Ser2Ser
- gnomAD 16-81785995-C-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.099
- CADD 2.59
- Population evidence available
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.177
- Literature evidence available