R41S (p.Arg41Ser) variant of PLCG2 (P16885)
R41S (p.Arg41Ser) in PLCG2 (P16885) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R41S (p.Arg41Ser) variant details
- p.Arg41Ser
- gnomAD 16-81786112-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.53
- CADD 24.00
- PolyPhen-2 0.39
- SIFT 0.01
- Population evidence available
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.557
- Literature evidence available