L24V (p.Leu24Val) variant of PLCG2 (P16885)
L24V (p.Leu24Val) in PLCG2 (P16885) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L24V (p.Leu24Val) variant details
- p.Leu24Val
- gnomAD 16-81786059-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.627
- CADD 20.30
- PolyPhen-2 0.29
- SIFT 0.36
- Population evidence available
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score 0.0409
- Literature evidence available