K35K (p.Lys35Lys) variant of PLCG2 (P16885)
K35K (p.Lys35Lys) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
K35K (p.Lys35Lys) variant details
- p.Lys35Lys
- rs1910957870
- gnomAD 16-81786094-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.32
- CADD 10.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score 0.0593
- Literature evidence available