K15K (p.Lys15Lys) variant of PLCG2 (P16885)
K15K (p.Lys15Lys) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
K15K (p.Lys15Lys) variant details
- p.Lys15Lys
- rs1173675944
- gnomAD 16-81786034-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.355
- CADD 10.50
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.254
- Literature evidence available