I18I (p.Ile18Ile) variant of PLCG2 (P16885)
I18I (p.Ile18Ile) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
I18I (p.Ile18Ile) variant details
- p.Ile18Ile
- rs1486559662
- gnomAD 16-81786043-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.407
- CADD 12.10
- Population evidence available
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.936
- Literature evidence available