G25G (p.Gly25Gly) variant of PLCG2 (P16885)
G25G (p.Gly25Gly) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G25G (p.Gly25Gly) variant details
- p.Gly25Gly
- gnomAD 16-81786064-G-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.252
- CADD 8.80
- Population evidence available
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.894
- Literature evidence available