F33F (p.Phe33Phe) variant of PLCG2 (P16885)
F33F (p.Phe33Phe) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
F33F (p.Phe33Phe) variant details
- p.Phe33Phe
- rs760188007
- gnomAD 16-81786088-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.395
- CADD 10.40
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.293
- Literature evidence available