F31F (p.Phe31Phe) variant of PLCG2 (P16885)
F31F (p.Phe31Phe) in PLCG2 (P16885) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
F31F (p.Phe31Phe) variant details
- p.Phe31Phe
- rs1910956931
- gnomAD 16-81786082-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.456
- CADD 13.20
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- PLCG2 SH3 domain domainome 1.0: score -0.0504
- Literature evidence available