D59N (p.Asp59Asn) variant of PLCG2 (P16885)
D59N (p.Asp59Asn) in PLCG2 (P16885) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data, published literature, and structural context.
D59N (p.Asp59Asn) variant details
- p.Asp59Asn
- gnomAD 16-81786164-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.735
- CADD 24.00
- PolyPhen-2 0.08
- SIFT 0.12
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available
- Literature evidence available