D59E (p.Asp59Glu) variant of PLCG2 (P16885)
D59E (p.Asp59Glu) in PLCG2 (P16885) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
D59E (p.Asp59Glu) variant details
- p.Asp59Glu
- TOPMed rs1396122255
- gnomAD rs1396122255
- Missense
- Variant Prioritization Score for Impact Estimate 0.497
- CADD 23.10
- PolyPhen-2 0.66
- SIFT 0.23
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available