A58S (p.Ala58Ser) variant of PLCG2 (P16885)
A58S (p.Ala58Ser) in PLCG2 (P16885) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
A58S (p.Ala58Ser) variant details
- p.Ala58Ser
- gnomAD 16-81786161-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.642
- CADD 22.80
- PolyPhen-2 0.31
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available