Y168C (p.Tyr168Cys) variant of PKP2 (Plakophilin-2)
Y168C (p.Tyr168Cys) in PKP2 (Plakophilin-2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions and structural context.
Y168C (p.Tyr168Cys) variant details
- p.Tyr168Cys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.56
- MetaSVM -0.46
- SIFT 0.02
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available