C33* (p.Cys33Ter) variant of PKD1 (Polycystin-1)

C33* (p.Cys33Ter) in PKD1 (Polycystin-1) is a protein-truncating change. Clinical records from EBI and UniProt describe it as pathogenic. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.

C33* (p.Cys33Ter) variant details