V25I (p.Val25Ile) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
V25I (p.Val25Ile) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
V25I (p.Val25Ile) variant details
- p.Val25Ile
- 1000Genomes rs117136501
- ExAC rs117136501
- gnomAD rs117136501
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.03
- AlphaMissense 0.11
- MetaLR 0.01
- MetaSVM -0.94
- CADD 14.10
- PolyPhen-2 0.37
- Most common in the 1KG:CEU population (allele frequency 0.0042)
- Structural context available