V23E (p.Val23Glu) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
V23E (p.Val23Glu) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
V23E (p.Val23Glu) variant details
- p.Val23Glu
- gnomAD 9-5534757-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.371
- REVEL 0.34
- AlphaMissense 0.91
- MetaLR 0.05
- MetaSVM -1.17
- CADD 27.60
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available