T24I (p.Thr24Ile) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
T24I (p.Thr24Ile) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
T24I (p.Thr24Ile) variant details
- p.Thr24Ile
- TOPMed rs1320163307
- gnomAD rs1320163307
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.07
- AlphaMissense 0.18
- MetaLR 0.02
- MetaSVM -1.02
- CADD 22.30
- PolyPhen-2 0.99
- Most common in the Latino/Admixed American population (allele frequency 0.002)
- Structural context available