T22A (p.Thr22Ala) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
T22A (p.Thr22Ala) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
T22A (p.Thr22Ala) variant details
- p.Thr22Ala
- TOPMed rs768189989
- gnomAD rs768189989
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.17
- AlphaMissense 0.16
- MetaLR 0.02
- MetaSVM -1.16
- CADD 23.30
- PolyPhen-2 0.89
- Most common in the REMAINING population (allele frequency 6.7e-05)
- Structural context available