S9R (p.Ser9Arg) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
S9R (p.Ser9Arg) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
S9R (p.Ser9Arg) variant details
- p.Ser9Arg
- TOPMed rs1820296181
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.18
- AlphaMissense 0.39
- MetaLR 0.04
- MetaSVM -1.04
- CADD 20.80
- PolyPhen-2 0.91
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available