S36R (p.Ser36Arg) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
S36R (p.Ser36Arg) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S36R (p.Ser36Arg) variant details
- p.Ser36Arg
- TOPMed rs992575112
- gnomAD rs992575112
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.16
- AlphaMissense 0.35
- MetaLR 0.03
- MetaSVM -1.10
- CADD 24.20
- PolyPhen-2 1.00
- Most common in the African/African-American population (allele frequency 0.00017)
- Structural context available