L4R (p.Leu4Arg) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
L4R (p.Leu4Arg) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
L4R (p.Leu4Arg) variant details
- p.Leu4Arg
- Ensembl rs990619741
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.24
- AlphaMissense 0.19
- MetaLR 0.06
- MetaSVM -1.07
- CADD 24.00
- PolyPhen-2 1.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available