L4F (p.Leu4Phe) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
L4F (p.Leu4Phe) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L4F (p.Leu4Phe) variant details
- p.Leu4Phe
- gnomAD rs1820295845
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.12
- AlphaMissense 0.07
- MetaLR 0.06
- MetaSVM -1.06
- CADD 18.60
- PolyPhen-2 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available