L40P (p.Leu40Pro) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
L40P (p.Leu40Pro) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
L40P (p.Leu40Pro) variant details
- p.Leu40Pro
- gnomAD rs1406771137
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.41
- AlphaMissense 0.94
- MetaLR 0.09
- MetaSVM -1.07
- CADD 25.10
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available