L10M (p.Leu10Met) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
L10M (p.Leu10Met) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L10M (p.Leu10Met) variant details
- p.Leu10Met
- TOPMed rs1416485350
- gnomAD rs1416485350
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.10
- AlphaMissense 0.10
- MetaLR 0.05
- MetaSVM -1.05
- CADD 23.30
- PolyPhen-2 1.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available