K27R (p.Lys27Arg) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
K27R (p.Lys27Arg) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
K27R (p.Lys27Arg) variant details
- p.Lys27Arg
- ExAC rs777689711
- TOPMed rs777689711
- gnomAD rs777689711
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.07
- AlphaMissense 0.09
- MetaLR 0.02
- MetaSVM -1.04
- CADD 22.10
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 3.9e-05)
- Structural context available