K27N (p.Lys27Asn) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
K27N (p.Lys27Asn) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
K27N (p.Lys27Asn) variant details
- p.Lys27Asn
- Ensembl rs2129792176
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.05
- AlphaMissense 0.55
- MetaLR 0.03
- MetaSVM -1.10
- CADD 23.20
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available