I32T (p.Ile32Thr) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
I32T (p.Ile32Thr) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
I32T (p.Ile32Thr) variant details
- p.Ile32Thr
- ESP rs369302753
- ExAC rs369302753
- TOPMed rs369302753
- gnomAD rs369302753
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.05
- AlphaMissense 0.06
- MetaLR 0.02
- MetaSVM -1.01
- CADD 20.30
- PolyPhen-2 0.04
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available