I32R (p.Ile32Arg) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
I32R (p.Ile32Arg) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
I32R (p.Ile32Arg) variant details
- p.Ile32Arg
- ESP rs369302753
- ExAC rs369302753
- TOPMed rs369302753
- gnomAD rs369302753
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.09
- AlphaMissense 0.21
- MetaLR 0.02
- MetaSVM -1.05
- CADD 21.40
- PolyPhen-2 0.30
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available