I31V (p.Ile31Val) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
I31V (p.Ile31Val) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
I31V (p.Ile31Val) variant details
- p.Ile31Val
- gnomAD 9-5534780-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0783
- REVEL 0.01
- AlphaMissense 0.07
- MetaLR 0.01
- MetaSVM -1.00
- CADD 0.19
- PolyPhen-2 0.01
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available