I31L (p.Ile31Leu) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
I31L (p.Ile31Leu) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
I31L (p.Ile31Leu) variant details
- p.Ile31Leu
- gnomAD rs1411122146
- Missense
- Variant Prioritization Score for Impact Estimate 0.0863
- REVEL 0.01
- AlphaMissense 0.10
- MetaLR 0.01
- MetaSVM -1.01
- CADD 4.77
- PolyPhen-2 0.04
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available