I2M (p.Ile2Met) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
I2M (p.Ile2Met) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
I2M (p.Ile2Met) variant details
- p.Ile2Met
- Ensembl rs2129725821
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- REVEL 0.04
- AlphaMissense 0.10
- MetaLR 0.01
- MetaSVM -0.99
- CADD 6.61
- PolyPhen-2 0.16
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available