I17V (p.Ile17Val) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
I17V (p.Ile17Val) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
I17V (p.Ile17Val) variant details
- p.Ile17Val
- gnomAD 9-5522595-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.102
- REVEL 0.01
- AlphaMissense 0.08
- MetaLR 0.01
- MetaSVM -0.98
- CADD 1.28
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available