I17T (p.Ile17Thr) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
I17T (p.Ile17Thr) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
I17T (p.Ile17Thr) variant details
- p.Ile17Thr
- TOPMed rs941236320
- gnomAD rs941236320
- Missense
- Variant Prioritization Score for Impact Estimate 0.0794
- REVEL 0.02
- AlphaMissense 0.05
- MetaLR 0.01
- MetaSVM -0.97
- CADD 0.06
- PolyPhen-2 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available