I17R (p.Ile17Arg) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
I17R (p.Ile17Arg) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
I17R (p.Ile17Arg) variant details
- p.Ile17Arg
- TOPMed rs941236320
- gnomAD rs941236320
- Missense
- Variant Prioritization Score for Impact Estimate 0.0829
- REVEL 0.02
- AlphaMissense 0.10
- MetaLR 0.02
- MetaSVM -1.02
- CADD 0.97
- PolyPhen-2 0.01
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available