I17M (p.Ile17Met) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
I17M (p.Ile17Met) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
I17M (p.Ile17Met) variant details
- p.Ile17Met
- gnomAD 9-5522597-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.03
- AlphaMissense 0.07
- MetaLR 0.02
- MetaSVM -1.03
- CADD 11.00
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available