H34R (p.His34Arg) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
H34R (p.His34Arg) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
H34R (p.His34Arg) variant details
- p.His34Arg
- Ensembl rs1820548187
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.09
- AlphaMissense 0.12
- MetaLR 0.02
- MetaSVM -1.03
- CADD 16.30
- PolyPhen-2 0.64
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available