H34Q (p.His34Gln) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
H34Q (p.His34Gln) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
H34Q (p.His34Gln) variant details
- p.His34Gln
- gnomAD rs1820548258
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.09
- AlphaMissense 0.21
- MetaLR 0.03
- MetaSVM -0.98
- CADD 17.00
- PolyPhen-2 0.78
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available