G35S (p.Gly35Ser) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
G35S (p.Gly35Ser) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G35S (p.Gly35Ser) variant details
- p.Gly35Ser
- Ensembl rs2129792538
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.14
- AlphaMissense 0.19
- MetaLR 0.07
- MetaSVM -0.88
- CADD 24.00
- PolyPhen-2 0.91
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available