G35A (p.Gly35Ala) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
G35A (p.Gly35Ala) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G35A (p.Gly35Ala) variant details
- p.Gly35Ala
- Ensembl rs1820548308
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.17
- AlphaMissense 0.36
- MetaLR 0.09
- MetaSVM -0.77
- CADD 24.40
- PolyPhen-2 0.99
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available