F21C (p.Phe21Cys) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
F21C (p.Phe21Cys) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
F21C (p.Phe21Cys) variant details
- p.Phe21Cys
- Ensembl rs2129791886
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.27
- AlphaMissense 0.92
- MetaLR 0.04
- MetaSVM -1.21
- CADD 28.70
- PolyPhen-2 1.00
- Most common in the HGDP:NAXI population (allele frequency 0.071)
- Structural context available