E41D (p.Glu41Asp) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
E41D (p.Glu41Asp) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
E41D (p.Glu41Asp) variant details
- p.Glu41Asp
- ExAC rs762452068
- gnomAD rs762452068
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.24
- AlphaMissense 0.45
- MetaLR 0.08
- MetaSVM -0.96
- CADD 23.20
- PolyPhen-2 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available