E33Q (p.Glu33Gln) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
E33Q (p.Glu33Gln) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
E33Q (p.Glu33Gln) variant details
- p.Glu33Gln
- ESP rs373326879
- ExAC rs373326879
- gnomAD rs373326879
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.07
- AlphaMissense 0.18
- MetaLR 0.05
- MetaSVM -1.09
- CADD 23.40
- PolyPhen-2 0.89
- Most common in the East Asian population (allele frequency 0.00018)
- Structural context available