E33K (p.Glu33Lys) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
E33K (p.Glu33Lys) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
E33K (p.Glu33Lys) variant details
- p.Glu33Lys
- ESP rs373326879
- ExAC rs373326879
- gnomAD rs373326879
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.06
- AlphaMissense 0.22
- MetaLR 0.04
- MetaSVM -1.08
- CADD 22.90
- PolyPhen-2 0.80
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available