E33D (p.Glu33Asp) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
E33D (p.Glu33Asp) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
E33D (p.Glu33Asp) variant details
- p.Glu33Asp
- TOPMed rs1820548093
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.04
- AlphaMissense 0.09
- MetaLR 0.01
- MetaSVM -0.98
- CADD 1.21
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available