E28D (p.Glu28Asp) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
E28D (p.Glu28Asp) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
E28D (p.Glu28Asp) variant details
- p.Glu28Asp
- ExAC rs770000726
- gnomAD rs770000726
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.06
- AlphaMissense 0.14
- MetaLR 0.01
- MetaSVM -0.95
- CADD 14.30
- PolyPhen-2 0.21
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available