A19V (p.Ala19Val) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
A19V (p.Ala19Val) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
A19V (p.Ala19Val) variant details
- p.Ala19Val
- gnomAD 9-5534745-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.14
- AlphaMissense 0.39
- MetaLR 0.05
- MetaSVM -1.10
- CADD 23.20
- PolyPhen-2 0.92
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available