A19T (p.Ala19Thr) variant of PDCD1LG2 (Programmed cell death 1 ligand 2)
A19T (p.Ala19Thr) in PDCD1LG2 (Programmed cell death 1 ligand 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A19T (p.Ala19Thr) variant details
- p.Ala19Thr
- Ensembl rs1820296746
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.12
- AlphaMissense 0.33
- MetaLR 0.05
- MetaSVM -1.03
- CADD 33.00
- PolyPhen-2 0.98
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available